The primary focus of the book is on the practical difficulties one often faces when dealing with patients with acute coronary syndrome and specific comorbidities. It provides clear solutions to each problem, based on a thorough but succinct review of the state-of-the-art and the latest guidelines. Every chapter can guide one when faced with “associated comorbid conditions with acute coronary syndrome”. It is unique compilation of challenging case scenarios and dilemmas in cardio-vascular medicine. It discusses each case/topic, its complexity in a most lucid manner with extensive coverage of the relevant literature. The selection of cases and the topics explore those areas of cardiology which remains untouched in textbooks, journals and even conferences.