This book is designed to familiarize general urologists with the care of transgender and gender non-conforming individuals. Written by experts in reconstructive urology, it characterizes the process of gender affirmation and explains the surgical anatomy of both feminizing and masculinizing gender-affirming procedures including vaginoplasty, orchiectomy, hysterectomy, vaginectomy, phalloplasty, metoidioplasty, and prosthetics. Guiding the clinician in identification of immediate and long-term risks of gender-affirming surgery, it instructs clinicians in endocrinological care, options for fertility preservation, evaluation of malignancies after hormonal therapy, appropriate postsurgical follow-up, and the management of common complications involving urethral stricture, fistula, neo-vaginal stenosis, and incontinence.