The first part discusses the ROSE procedure, clarifying the role of ROSE in the diagnosis of respiratory diseases, while further sections address correct work processes and the implications of ROSE, incorporating multidisciplinary perspectives on respiratory diseases, interventional pulmonology, pathology, clinical microbiology and infectious diseases. This helps practitioners, such as pulmonologists, interventional physicians, radiologists, critical care physicians, haematologists and rheumatologists, establish standardized clinical practices. The book also covers detailed clinical workups, including presentations of lesions, which are of interest to physicians from other specialties.