by Michele Ghidini (Author)

Principles of Immunotherapy in Breast and Gastrointestinal Cancers: Activity, Mechanisms of Resistance and New Sensitization Strategies presents updated research findings on immunotherapy, with special focus on the mechanisms of resistance of those cancer types and how to overcome them.

The book discusses topics such as tumor cell-intrinsic and extrinsic mechanisms of cancer resistance to immunotherapy; the role of currently available biomarkers; strategies to overcome therapeutic resistance; sensitizing agents for cancer resistance to cell mediated immunotherapy; and Immunotherapeutic approaches, mechanisms of resistance and sensitizing strategies in gastroesophageal and biliopancreatic tumors and colorectal cancer.

It is a valuable resource for researchers, students and members of the biomedical and medical fields who want to learn more about resistance to immunotherapy and how to overcome it.

Presents relevant findings on immunotherapy for breast and GI cancer types in a synthetic and didactic way for easy consult

Describes resistance mechanisms of those cancer types and how to overcome them to improve immunotherapy outcomes

Encompasses several diagrams and figures to help readers get a clearer picture of the research findings and how they can be applied to the clinical setting