By DLM Gregory R. Halverson, MT(ASCP)SBB
Since the publication in 1980 of the slim AABB volume on the topic, much has changed. This update covers several new types of polyagglutination as well as some of the cell markers that have become associated with polyagglutination and disease. The intervening 40+ years of change have presented today’s professionals with new challenges, including the predominance of monoclonal, rather than polyclonal, reagents; lack of commercial sources of lectins; and a need to understand glycan array chips and computer-generated data analysis. Topics include: Lectins Acquired Polyagglutination Inherited and Rare Forms Identification of TR Polyagglutination NOR Blood Group Antigen Transfusion Support for the Patient with Polyaggluination