This comprehensive book organizes the components of quality and safety outcomes, within a framework developed by expert nurses. Such a framework is missing in existing books on quality and safety in health care, and the concepts of nursing and organizational outcomes are often overlooked. This book fills this gap by exploring and expanding the various features of the Quality Health Outcomes Model (QHOM) and its four main concepts of System, Client, Interventions, and Outcomes. Using a broad and comprehensive approach, the authors identify the most current empirical evidence and concepts in the nursing field to provide an up-to-date understanding of the QHOM’s four concepts and their interrelations. New concepts include (a) systems concepts of turbulence and complexity of workflow and use of the electronic health record to support clinical workflow; (b) client concepts of social determinants of health, health literacy, and chronicity; (c) intervention concepts of interprofessional practice, nursing care processes including unfinished care, and care coordination; (d) outcome concepts related to nursing and the organization in addition to patient outcomes that includes the patients’ experience.