This is a book of case series on interventional bronchoscopy and pleuroscopy based on decades of clinical experience of the authors. The purpose of this publication is not to provide the principles, theory or evidence of clinical practice of these procedures but to illustrate actual case scenarios. Each case is presented with the history, including clinical, radiological, endoscopic findings and final outcome; and procedural details in the form of video illustration. Learning points of these cases are highlighted either at the end of the case presentation and/or in a separate chapter. Physicians accessing the immense resource of videos will acquire the knowledge and expertise necessary to manage their patients.