Essentials of Biostatistics in Public Health, Fourth Edition provides a fundamental and engaging background for students learning to apply and appropriately interpret biostatistics applications in the field of public health. Many examples are drawn directly from the author’s remarkable clinical experiences with the renowned Framingham Heart Study, making this text practical, interesting, and accessible for those with little mathematical background. The examples are real, relevant, and manageable in size so that students can easily focus on applications rather than become overwhelmed by computations. The Fourth Edition has been thoroughly updated, and now offers a new chapter on career opportunities and new case studies in each chapter focused on COVID-19. This edition will also include free access to JMP Student Edition Software, which is a streamlined version of SAS’ statistical discovery software and is well-suited to for introductory or intermediate statistics courses.