By Damien Glaive

Most anesthesia texts teach you what to do. This one teaches you why and why it matters most when the patient has no margin for error.

Anesthesia in High-Risk Patients is a clinical reference built around one premise: the patients who suffer the worst perioperative outcomes are not victims of technique failures. They are patients whose physiology was misread, underestimated, or managed with an approach designed for someone else.

Across focused chapters, it covers every major high-risk category in modern practice:

Ischemic heart disease, heart failure, valvular lesions, arrhythmias, and cardiac devices

Anemia, coagulopathy, anticoagulation bridging, and massive transfusion protocols

COPD, OSA, obesity hypoventilation, difficult airway, and one-lung ventilation

CKD drug dosing, cirrhosis pharmacokinetics, and hepatorenal syndrome

Perioperative glycemic control, pheochromocytoma, thyroid storm, and adrenal crisis

The frail elderly, the obstetric patient, the neonate, and the neurologically impaired

Damage control anesthesia, sepsis management, and failure-to-rescue frameworks

Regional anesthesia as a risk-reduction strategy with full ASRA anticoagulation timing

Every chapter includes a key terminology table, pathophysiology-to-management narrative, composite clinical case study, and clinical pearls. The book closes with a 200+ term glossary and seven clinical reference appendices covering drug dosing, scoring tools, and monitoring protocols.

For anesthesiology residents, CRNAs, and attending clinicians who need a focused, evidence-grounded reference for the cases that demand more than a standard approach.