Alzheimer's

disease (AD) is the leading cause of dementia and, unfortunately,

remains incurable. The social, emotional and financial implications of

AD are immeasurable, and about 47 million people worldwide are affected

by AD or other forms of dementia. As lifespans are improved by

healthcare systems worldwide, age-associated neurodegenerative diseases

are imposing an increasing challenge to science. It is becoming

imperative for us to understand the causes of these diseases, AD in

particular, at molecular and cellular levels. Starting with the broader

picture from a biological perspective, this book takes the reader

through fascinating dynamics within and outside of neurons in the

brain.Alzheimer's Disease: Biology, Biophysics and Computational Models

helps the reader to understand AD from mechanistic and biochemical

perspectives at intra- and inter-cellular levels. It focuses on

biochemical pathways and modeling associated with AD. Some of the recent

research on biophysics and computational models related to AD are

explained using context-driven computational and mathematical modeling

and essential biology is discussed to understand the modeling research